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4axl

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{{STRUCTURE_4axl| PDB=4axl | SCENE= }}
{{STRUCTURE_4axl| PDB=4axl | SCENE= }}
===HUMAN CATHEPSIN L APO FORM WITH ZN===
===HUMAN CATHEPSIN L APO FORM WITH ZN===
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{{ABSTRACT_PUBMED_23658062}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4axl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXL OCA].
[[4axl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXL OCA].
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==Reference==
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<ref group="xtra">PMID:023658062</ref><references group="xtra"/><references/>
[[Category: Cathepsin L]]
[[Category: Cathepsin L]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 17:57, 19 June 2013

Template:STRUCTURE 4axl

Contents

HUMAN CATHEPSIN L APO FORM WITH ZN

Template:ABSTRACT PUBMED 23658062

Function

[CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.

About this Structure

4axl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ehmke V, Winkler E, Banner DW, Haap W, Schweizer WB, Rottmann M, Kaiser M, Freymond C, Schirmeister T, Diederich F. Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human Cathepsin L. ChemMedChem. 2013 Jun;8(6):967-75. doi: 10.1002/cmdc.201300112. Epub 2013 May 9. PMID:23658062 doi:10.1002/cmdc.201300112

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