4kgn
From Proteopedia
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| - | + | ==Crystal structure of a tRNA (cytidine(34)-2'-O)-methyltransferase bound to S-adenosyl homocysteine== | |
| - | + | <StructureSection load='4kgn' size='340' side='right' caption='[[4kgn]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4kgn]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei_1710b Burkholderia pseudomallei 1710b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KGN FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e5y|3e5y]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BURPS1710b_0668, trmL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=320372 Burkholderia pseudomallei 1710b])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(cytidine(34)-2'-O)-methyltransferase tRNA (cytidine(34)-2'-O)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.207 2.1.1.207] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kgn RCSB], [http://www.ebi.ac.uk/pdbsum/4kgn PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/Q3JWH1_BURP1 Q3JWH1_BURP1]] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity).[HAMAP-Rule:MF_01885] | [[http://www.uniprot.org/uniprot/Q3JWH1_BURP1 Q3JWH1_BURP1]] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity).[HAMAP-Rule:MF_01885] | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[TRNA methyltransferase|TRNA methyltransferase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Burkholderia pseudomallei 1710b]] | [[Category: Burkholderia pseudomallei 1710b]] | ||
| - | [[Category: | + | [[Category: Structural genomic]] |
[[Category: Half-site occupancy]] | [[Category: Half-site occupancy]] | ||
[[Category: National institute for allergy and infectious disease]] | [[Category: National institute for allergy and infectious disease]] | ||
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[[Category: Sah]] | [[Category: Sah]] | ||
[[Category: Sam]] | [[Category: Sam]] | ||
| - | [[Category: Seattle structural genomics center for infectious disease]] | ||
[[Category: Ssgcid]] | [[Category: Ssgcid]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Trefoil protein knot]] | [[Category: Trefoil protein knot]] | ||
[[Category: Trna methyltransferase]] | [[Category: Trna methyltransferase]] | ||
Revision as of 06:09, 25 December 2014
Crystal structure of a tRNA (cytidine(34)-2'-O)-methyltransferase bound to S-adenosyl homocysteine
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