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3ptd

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Template:STRUCTURE 3ptd

Contents

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D274S

Template:ABSTRACT PUBMED 9335537

Function

[PLC_BACCE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.

About this Structure

3ptd is a 1 chain structure with sequence from Bacillus cereus. Full crystallographic information is available from OCA.

Reference

  • Gassler CS, Ryan M, Liu T, Griffith OH, Heinz DW. Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis. Biochemistry. 1997 Oct 21;36(42):12802-13. PMID:9335537 doi:10.1021/bi971102d

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OCA

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