This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3qr5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_3qr5| PDB=3qr5 | SCENE= }}
+
==Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted==
-
===Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted===
+
<StructureSection load='3qr5' size='340' side='right' caption='[[3qr5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[3qr5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QR5 FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/Q9ERN6_MOUSE Q9ERN6_MOUSE]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3im5|3im5]]</td></tr>
-
 
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ryr2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qr5 RCSB], [http://www.ebi.ac.uk/pdbsum/3qr5 PDBsum]</span></td></tr>
-
[[3qr5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR5 OCA].
+
</table>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<references group="xtra"/><references/>
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Lobo, P A.]]
+
[[Category: Lobo, P A]]
-
[[Category: Petegem, F Van.]]
+
[[Category: Petegem, F Van]]
[[Category: Beta trefoil]]
[[Category: Beta trefoil]]
[[Category: Sarcoplasmic reticulum]]
[[Category: Sarcoplasmic reticulum]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]

Revision as of 10:35, 19 December 2014

Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted

3qr5, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3qr5"
Personal tools