3pva

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m (Protected "3pva" [edit=sysop:move=sysop])
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{{STRUCTURE_3pva| PDB=3pva | SCENE= }}
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==PENICILLIN V ACYLASE FROM B. SPHAERICUS==
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===PENICILLIN V ACYLASE FROM B. SPHAERICUS===
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<StructureSection load='3pva' size='340' side='right' caption='[[3pva]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3pva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PVA FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/PAC_BACSH PAC_BACSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pva RCSB], [http://www.ebi.ac.uk/pdbsum/3pva PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3pva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA].
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/3pva_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Penicillin acylase|Penicillin acylase]]
*[[Penicillin acylase|Penicillin acylase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010331865</ref><references group="xtra"/><references/>
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[[Category: Lysinibacillus sphaericus]]
[[Category: Lysinibacillus sphaericus]]
[[Category: Penicillin amidase]]
[[Category: Penicillin amidase]]
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[[Category: Brannigan, J A.]]
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[[Category: Brannigan, J A]]
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[[Category: Dauter, Z.]]
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[[Category: Dauter, Z]]
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[[Category: Dodson, E J.]]
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[[Category: Dodson, E J]]
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[[Category: Dodson, G G.]]
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[[Category: Dodson, G G]]
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[[Category: Mcvey, C E.]]
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[[Category: Mcvey, C E]]
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[[Category: Pundle, A V.]]
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[[Category: Pundle, A V]]
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[[Category: Rao, K N.]]
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[[Category: Rao, K N]]
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[[Category: Sivaraman, H.]]
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[[Category: Sivaraman, H]]
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[[Category: Suresh, C G.]]
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[[Category: Suresh, C G]]
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[[Category: Verma, C S.]]
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[[Category: Verma, C S]]
[[Category: Amidohydrolase]]
[[Category: Amidohydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Ntn hydrolase]]
[[Category: Ntn hydrolase]]
[[Category: Penicillin v acylase]]
[[Category: Penicillin v acylase]]

Revision as of 11:12, 19 December 2014

PENICILLIN V ACYLASE FROM B. SPHAERICUS

3pva, resolution 2.80Å

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