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2gic
From Proteopedia
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| - | [[Image:2gic.gif|left|200px]] | + | [[Image:2gic.gif|left|200px]] |
| - | + | ||
| - | '''Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex''' | + | {{Structure |
| + | |PDB= 2gic |SIZE=350|CAPTION= <scene name='initialview01'>2gic</scene>, resolution 2.920Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=IUM:URANYL (VI) ION'>IUM</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11277 Vesicular stomatitis Indiana virus]) | ||
| + | }} | ||
| + | |||
| + | '''Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2GIC is a [ | + | 2GIC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vesicular_stomatitis_indiana_virus Vesicular stomatitis indiana virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIC OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of the vesicular stomatitis virus nucleoprotein-RNA complex., Green TJ, Zhang X, Wertz GW, Luo M, Science. 2006 Jul 21;313(5785):357-60. Epub 2006 Jun 15. PMID:[http:// | + | Structure of the vesicular stomatitis virus nucleoprotein-RNA complex., Green TJ, Zhang X, Wertz GW, Luo M, Science. 2006 Jul 21;313(5785):357-60. Epub 2006 Jun 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16778022 16778022] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Vesicular stomatitis indiana virus]] | [[Category: Vesicular stomatitis indiana virus]] | ||
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[[Category: protein-rna complex]] | [[Category: protein-rna complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:05:00 2008'' |
Revision as of 15:05, 20 March 2008
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| , resolution 2.920Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | N (Vesicular stomatitis Indiana virus) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of a vesicular stomatitis virus nucleocapsid-RNA complex
Overview
Vesicular stomatitis virus is a negative-stranded RNA virus. Its nucleoprotein (N) binds the viral genomic RNA and is involved in multiple functions including transcription, replication, and assembly. We have determined a 2.9 angstrom structure of a complex containing 10 molecules of the N protein and 90 bases of RNA. The RNA is tightly sequestered in a cavity at the interface between two lobes of the N protein. This serves to protect the RNA in the absence of polynucleotide synthesis. For the RNA to be accessed, some conformational change in the N protein should be necessary.
About this Structure
2GIC is a Single protein structure of sequence from Vesicular stomatitis indiana virus. Full crystallographic information is available from OCA.
Reference
Structure of the vesicular stomatitis virus nucleoprotein-RNA complex., Green TJ, Zhang X, Wertz GW, Luo M, Science. 2006 Jul 21;313(5785):357-60. Epub 2006 Jun 15. PMID:16778022
Page seeded by OCA on Thu Mar 20 17:05:00 2008
