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2m7f

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'''Unreleased structure'''
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{{STRUCTURE_2m7f| PDB=2m7f | SCENE= }}
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===The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions===
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The entry 2m7f is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
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Authors: Chuang, W., Chang, Y.
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==About this Structure==
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[[2m7f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7F OCA].
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Description: The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions
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[[Category: Calloselasma rhodostoma]]
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[[Category: Chang, Y.]]
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[[Category: Chuang, W.]]
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[[Category: C-terminal region mutation]]
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[[Category: Hydrolase]]
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[[Category: Rgd motif]]
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[[Category: Rhodostomin mutant protein]]

Revision as of 06:22, 20 June 2013

Template:STRUCTURE 2m7f

The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions

Function

[VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).

About this Structure

2m7f is a 1 chain structure with sequence from Calloselasma rhodostoma. Full experimental information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

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