4blu

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m (Protected "4blu" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4blu| PDB=4blu | SCENE= }}
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===Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ===
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The entry 4blu is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/RLMJ_ECOLI RLMJ_ECOLI]] Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.<ref>PMID:16707682</ref> <ref>PMID:22847818</ref>
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Authors: Punekar, A.S., Liljeruhm, J., Shepherd, T.R., Forster, A.C., Selmer, M.
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==About this Structure==
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[[4blu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BLU OCA].
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Description: Crystal structure of Escherichia coli 23S rRNA (A2030-N6)-methyltransferase RlmJ
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Escherichia coli k-12]]
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[[Category: Forster, A C.]]
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[[Category: Liljeruhm, J.]]
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[[Category: Punekar, A S.]]
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[[Category: Selmer, M.]]
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[[Category: Shepherd, T R.]]
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[[Category: N6-methyladenine]]
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[[Category: Rossmann-like fold]]
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[[Category: Subdomain insertion]]
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[[Category: Transferase]]

Revision as of 08:31, 21 August 2013

Template:STRUCTURE 4blu

Contents

Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ

Function

[RLMJ_ECOLI] Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.[1] [2]

About this Structure

4blu is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  1. ↑ Palchevskiy V, Finkel SE. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. J Bacteriol. 2006 Jun;188(11):3902-10. PMID:16707682 doi:10.1128/JB.01974-05
  2. ↑ Golovina AY, Dzama MM, Osterman IA, Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA. The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA. RNA. 2012 Sep;18(9):1725-34. doi: 10.1261/rna.034207.112. Epub 2012 Jul 30. PMID:22847818 doi:10.1261/rna.034207.112

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