This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4k6m
From Proteopedia
| Line 1: | Line 1: | ||
| - | + | {{STRUCTURE_4k6m| PDB=4k6m | SCENE= }} | |
| + | ===Crystal Structure of the full-length Japanese encephalitis virus NS5=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/Q5NT71_9FLAV Q5NT71_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | ||
| - | + | ==About this Structure== | |
| - | + | [[4k6m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_encephalitis_virus Japanese encephalitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6M OCA]. | |
| - | + | [[Category: Japanese encephalitis virus]] | |
| + | [[Category: Gong, P.]] | ||
| + | [[Category: Lu, G.]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Rna-dependent rna polymerase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 07:39, 28 August 2013
Crystal Structure of the full-length Japanese encephalitis virus NS5
Function
[Q5NT71_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
About this Structure
4k6m is a 2 chain structure with sequence from Japanese encephalitis virus. Full crystallographic information is available from OCA.
