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4k6m
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4k6m| PDB=4k6m | SCENE= }} | |
| + | ===Crystal Structure of the full-length Japanese encephalitis virus NS5=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/Q5NT71_9FLAV Q5NT71_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | ||
| - | + | ==About this Structure== | |
| - | + | [[4k6m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_encephalitis_virus Japanese encephalitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6M OCA]. | |
| - | + | [[Category: Japanese encephalitis virus]] | |
| + | [[Category: Gong, P.]] | ||
| + | [[Category: Lu, G.]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Rna-dependent rna polymerase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 07:39, 28 August 2013
Crystal Structure of the full-length Japanese encephalitis virus NS5
Function
[Q5NT71_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
About this Structure
4k6m is a 2 chain structure with sequence from Japanese encephalitis virus. Full crystallographic information is available from OCA.
