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4gzc

From Proteopedia

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==Reference==
==Reference==
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<references group="xtra"/><references/>
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<ref group="xtra">PMID:023553749</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae s288c]]
[[Category: Saccharomyces cerevisiae s288c]]
[[Category: Costakes, G T.]]
[[Category: Costakes, G T.]]

Revision as of 21:09, 19 June 2013

Template:STRUCTURE 4gzc

Contents

Crystal structure of yeast Ent2 ENTH domain

Template:ABSTRACT PUBMED 23553749

Function

[ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.[1]

About this Structure

4gzc is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  • Costakes GT, Sen A, Aguilar RC, Stauffacher CV. Crystallographic analysis of the ENTH domain from yeast epsin Ent2 that induces a cell division phenotype. Protein Sci. 2013 Mar 30. doi: 10.1002/pro.2259. PMID:23553749 doi:10.1002/pro.2259
  1. ↑ Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383

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OCA

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