4in4
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4in4| PDB=4in4 | SCENE= }} | {{STRUCTURE_4in4| PDB=4in4 | SCENE= }} | ||
===Crystal structure of cpd 15 bound to Keap1 Kelch domain=== | ===Crystal structure of cpd 15 bound to Keap1 Kelch domain=== | ||
| + | {{ABSTRACT_PUBMED_23647822}} | ||
==About this Structure== | ==About this Structure== | ||
[[4in4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_aureorectus Streptomyces aureorectus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IN4 OCA]. | [[4in4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_aureorectus Streptomyces aureorectus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IN4 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023647822</ref><references group="xtra"/><references/> | ||
[[Category: Streptomyces aureorectus]] | [[Category: Streptomyces aureorectus]] | ||
[[Category: Marcotte, D.]] | [[Category: Marcotte, D.]] | ||
[[Category: Silvian, L.]] | [[Category: Silvian, L.]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 15:44, 19 June 2013
Crystal structure of cpd 15 bound to Keap1 Kelch domain
Template:ABSTRACT PUBMED 23647822
About this Structure
4in4 is a 3 chain structure with sequence from Streptomyces aureorectus. Full crystallographic information is available from OCA.
Reference
- Marcotte D, Zeng W, Hus JC, McKenzie A, Hession C, Jin P, Bergeron C, Lugovskoy A, Enyedy I, Cuervo H, Wang D, Atmanene C, Roecklin D, Vecchi M, Vivat V, Kraemer J, Winkler D, Hong V, Chao J, Lukashev M, Silvian L. Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism. Bioorg Med Chem. 2013 Jul 15;21(14):4011-9. doi: 10.1016/j.bmc.2013.04.019. Epub , 2013 Apr 19. PMID:23647822 doi:10.1016/j.bmc.2013.04.019
