This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3qwp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_3qwp| PDB=3qwp | SCENE= }}
+
==Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1==
-
===Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1===
+
<StructureSection load='3qwp' size='340' side='right' caption='[[3qwp]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[3qwp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWP FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/SMYD3_HUMAN SMYD3_HUMAN]] Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.<ref>PMID:15235609</ref> <ref>PMID:22419068</ref>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
 
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMYD3, ZMYND1, ZNFN3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-
==About this Structure==
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] </span></td></tr>
-
[[3qwp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWP OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwp RCSB], [http://www.ebi.ac.uk/pdbsum/3qwp PDBsum]</span></td></tr>
-
 
+
</table>
-
==Reference==
+
__TOC__
-
<references group="xtra"/><references/>
+
</StructureSection>
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith, C H]]
-
[[Category: Bountra, C.]]
+
[[Category: Bountra, C]]
-
[[Category: Dombrovski, L.]]
+
[[Category: Dombrovski, L]]
-
[[Category: Dong, A.]]
+
[[Category: Dong, A]]
-
[[Category: Edwards, A M.]]
+
[[Category: Edwards, A M]]
-
[[Category: Li, Y.]]
+
[[Category: Li, Y]]
-
[[Category: Min, J.]]
+
[[Category: Min, J]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Structural genomic]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt, J]]
-
[[Category: Wernimont, A.]]
+
[[Category: Wernimont, A]]
-
[[Category: Wu, H.]]
+
[[Category: Wu, H]]
[[Category: Set and mynd domain]]
[[Category: Set and mynd domain]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Smyd3]]
[[Category: Smyd3]]
-
[[Category: Structural genomic]]
 
-
[[Category: Structural genomics consortium]]
 
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Zinc finger mynd domain-containing protein 1]]
[[Category: Zinc finger mynd domain-containing protein 1]]

Revision as of 10:23, 19 December 2014

Crystal structure of SET and MYND domain containing 3; Zinc finger MYND domain-containing protein 1

3qwp, resolution 1.53Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools