2w0c

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{{STRUCTURE_2w0c| PDB=2w0c | SCENE= }}
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==X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2==
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===X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2===
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<StructureSection load='2w0c' size='340' side='right' caption='[[2w0c]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
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{{ABSTRACT_PUBMED_18775333}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2w0c]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudoalteromonas_phage_pm2 Pseudoalteromonas phage pm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0C FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vvf|2vvf]], [[2vvd|2vvd]], [[2vve|2vve]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0c RCSB], [http://www.ebi.ac.uk/pdbsum/2w0c PDBsum]</span></td></tr>
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<table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w0/2w0c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Recent, primarily structural observations indicate that related viruses, harboring no sequence similarity, infect hosts of different domains of life. One such clade of viruses, defined by common capsid architecture and coat protein fold, is the so-called PRD1-adenovirus lineage. Here we report the structure of the marine lipid-containing bacteriophage PM2 determined by crystallographic analyses of the entire approximately 45 MDa virion and of the outer coat proteins P1 and P2, revealing PM2 to be a primeval member of the PRD1-adenovirus lineage with an icosahedral shell and canonical double beta barrel major coat protein. The view of the lipid bilayer, richly decorated with membrane proteins, constitutes a rare visualization of an in vivo membrane. The viral membrane proteins P3 and P6 are organized into a lattice, suggesting a possible assembly pathway to produce the mature virus.
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==Function==
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Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2.,Abrescia NG, Grimes JM, Kivela HM, Assenberg R, Sutton GC, Butcher SJ, Bamford JK, Bamford DH, Stuart DI Mol Cell. 2008 Sep 5;31(5):749-61. PMID:18775333<ref>PMID:18775333</ref>
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[[http://www.uniprot.org/uniprot/CAPSD_BPPM2 CAPSD_BPPM2]] Major capsid protein. [[http://www.uniprot.org/uniprot/SPIKE_BPPM2 SPIKE_BPPM2]] Receptor binding protein located at the fivefold vertices.
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==About this Structure==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[2w0c]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudoalteromonas_phage_pm2 Pseudoalteromonas phage pm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0C OCA].
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</div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:018775333</ref><ref group="xtra">PMID:016511151</ref><ref group="xtra">PMID:018082422</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Pseudoalteromonas phage pm2]]
[[Category: Pseudoalteromonas phage pm2]]
[[Category: Abrescia, N G.A.]]
[[Category: Abrescia, N G.A.]]

Revision as of 04:11, 3 October 2014

X-RAY STRUCTURE OF THE ENTIRE LIPID-CONTAINING BACTERIOPHAGE PM2

2w0c, resolution 7.00Å

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