3s19

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{{STRUCTURE_3s19| PDB=3s19 | SCENE= }}
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==Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0==
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===Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0===
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<StructureSection load='3s19' size='340' side='right' caption='[[3s19]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3s19]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S19 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/QUEF_VIBCH QUEF_VIBCH]] Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity).
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bp1|3bp1]], [[3rjb|3rjb]], [[3rj4|3rj4]], [[3rzp|3rzp]], [[3rzq|3rzq]]</td></tr>
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[[3s19]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S19 OCA].
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">queF, VC_0902 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/PreQ(1)_synthase PreQ(1) synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.13 1.7.1.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s19 RCSB], [http://www.ebi.ac.uk/pdbsum/3s19 PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Gu, M.]]
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[[Category: Gu, M]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Kim, Y.]]
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[[Category: Kim, Y]]
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[[Category: Zhou, M.]]
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[[Category: Zhou, M]]
[[Category: Alpha-beta structure]]
[[Category: Alpha-beta structure]]
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[[Category: Center for structural genomics of infectious disease]]
 
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Cytosol]]
[[Category: Cytosol]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Reductase]]
[[Category: Reductase]]
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[[Category: Structural genomic]]
 
[[Category: Tunneling fold]]
[[Category: Tunneling fold]]

Revision as of 10:29, 19 December 2014

Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0

3s19, resolution 1.50Å

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