3onr
From Proteopedia
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| - | + | ==Crystal structure of the calcium chelating immunodominant antigen, calcium dodecin (Rv0379),from Mycobacterium tuberculosis with a novel calcium-binding site== | |
| - | + | <StructureSection load='3onr' size='340' side='right' caption='[[3onr]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3onr]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ONR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ONR FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0379, secE2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3onr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3onr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3onr RCSB], [http://www.ebi.ac.uk/pdbsum/3onr PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | In eukaryotes, calcium-binding proteins play a pivotal role in diverse cellular processes, and recent findings suggest similar roles for bacterial proteins at different stages in their life cycle. Here, we report the crystal structure of calcium dodecin, Rv0379, from Mycobacterium tuberculosis with a dodecameric oligomeric assembly and a unique calcium-binding motif. Structure and sequence analysis identify the orthologs of Ca dodecins with different ligand-binding specificity. | ||
| - | + | Crystal structure of the calcium chelating immunodominant antigen, calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site.,Arockiasamy A, Aggarwal A, Savva CG, Holzenburg A, Sacchettini JC Protein Sci. 2011 Mar 2. doi: 10.1002/pro.607. PMID:21370306<ref>PMID:21370306</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Arulandu, A | + | [[Category: Arulandu, A]] |
| - | [[Category: Sacchettini, J C | + | [[Category: Sacchettini, J C]] |
[[Category: Calcium binding protein]] | [[Category: Calcium binding protein]] | ||
[[Category: Calcium dodecin]] | [[Category: Calcium dodecin]] | ||
Revision as of 07:22, 19 December 2014
Crystal structure of the calcium chelating immunodominant antigen, calcium dodecin (Rv0379),from Mycobacterium tuberculosis with a novel calcium-binding site
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