2lu9

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'''Unreleased structure'''
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{{STRUCTURE_2lu9| PDB=2lu9 | SCENE= }}
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===NMR solution structure of recombinant Tamapin===
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The entry 2lu9 is ON HOLD until Dec 07 2014
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==Function==
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[[http://www.uniprot.org/uniprot/KAX54_MESTA KAX54_MESTA]] Blocks small conductance calcium-activated potassium channels in pyramidal neurons of the hippocampus. Displays a unique, remarkable selectivity for SK2/KCNN2 versus SK1/KCNN1 and SK3/KCNN3 channels.<ref>PMID:12239213</ref>
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Authors: del Rio-Portilla, F., Ramirez-Cordero, B.
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==About this Structure==
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[[2lu9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LU9 OCA].
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Description: NMR solution structure of recombinant Tamapin
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Ramirez-Cordero, B.]]
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[[Category: Rio-Portilla, F del.]]
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[[Category: Cs alpha beta]]
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[[Category: Toxin]]

Revision as of 13:42, 11 December 2013

Template:STRUCTURE 2lu9

Contents

NMR solution structure of recombinant Tamapin

Function

[KAX54_MESTA] Blocks small conductance calcium-activated potassium channels in pyramidal neurons of the hippocampus. Displays a unique, remarkable selectivity for SK2/KCNN2 versus SK1/KCNN1 and SK3/KCNN3 channels.[1]

About this Structure

2lu9 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  1. ↑ Pedarzani P, D'hoedt D, Doorty KB, Wadsworth JD, Joseph JS, Jeyaseelan K, Kini RM, Gadre SV, Sapatnekar SM, Stocker M, Strong PN. Tamapin, a venom peptide from the Indian red scorpion (Mesobuthus tamulus) that targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neurons. J Biol Chem. 2002 Nov 29;277(48):46101-9. Epub 2002 Sep 17. PMID:12239213 doi:http://dx.doi.org/10.1074/jbc.M206465200

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