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4bpu

From Proteopedia

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m (Protected "4bpu" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4bpu| PDB=4bpu | SCENE= }}
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===Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain.===
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{{ABSTRACT_PUBMED_24043831}}
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The entry 4bpu is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
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Authors: Kilkenny, M.L., Perera, R.L., Pellegrini, L.
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==About this Structure==
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[[4bpu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPU OCA].
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Description: Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain.
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==Reference==
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<ref group="xtra">PMID:024043831</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Kilkenny, M L.]]
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[[Category: Pellegrini, L.]]
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[[Category: Perera, R L.]]
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[[Category: Dna-dependent rna polymerase]]
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[[Category: Transferase]]

Revision as of 08:08, 29 September 2013

Template:STRUCTURE 4bpu

Contents

Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain.

Template:ABSTRACT PUBMED 24043831

Function

[PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

About this Structure

4bpu is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kilkenny ML, Longo MA, Perera RL, Pellegrini L. Structures of human primase reveal design of nucleotide elongation site and mode of Pol alpha tethering. Proc Natl Acad Sci U S A. 2013 Sep 16. PMID:24043831 doi:10.1073/pnas.1311185110

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OCA

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