4j1l

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'''Unreleased structure'''
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{{STRUCTURE_4j1l| PDB=4j1l | SCENE= }}
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===Mutant Endotoxin TeNT===
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{{ABSTRACT_PUBMED_23994593}}
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The entry 4j1l is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TETX_CLOTE TETX_CLOTE]] Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
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Authors: Guo, J., Pan, X., Zhao, Y., Chen, S.
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==About this Structure==
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[[4j1l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1L OCA].
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Description: Mutant Endotoxin TeNT
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==Reference==
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<ref group="xtra">PMID:023994593</ref><references group="xtra"/><references/>
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[[Category: Tentoxilysin]]
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[[Category: Chen, S.]]
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[[Category: Guo, J.]]
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[[Category: Pan, X.]]
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[[Category: Zhao, Y.]]
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[[Category: Endotoxin]]
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[[Category: Toxin]]

Revision as of 11:02, 5 February 2014

Template:STRUCTURE 4j1l

Contents

Mutant Endotoxin TeNT

Template:ABSTRACT PUBMED 23994593

Function

[TETX_CLOTE] Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.

About this Structure

4j1l is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

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