4ksb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4ksb" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4ksb| PDB=4ksb | SCENE= }}
 +
===Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain===
-
The entry 4ksb is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>
-
Authors: Ward, A., Szewczyk, P., Grimard, V., Lee, C-W., Martinez, L., Doshi, R., Caya, A., Villaluz, M., Pardon, E., Cregger, C., Swartz, D.J., Falson, P., Urbatsch, I., Govaerts, C., Steyaert, J., Chang, G.
+
==About this Structure==
 +
[[4ksb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KSB OCA].
-
Description: Crystal structure of MDR transporter 1
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Mus musculus]]
 +
[[Category: Xenobiotic-transporting ATPase]]
 +
[[Category: Caya, A.]]
 +
[[Category: Chang, G.]]
 +
[[Category: Cregger, C.]]
 +
[[Category: Doshi, R.]]
 +
[[Category: Falson, P.]]
 +
[[Category: Govaerts, C.]]
 +
[[Category: Grimard, V.]]
 +
[[Category: Lee, C-W.]]
 +
[[Category: Martinez, L.]]
 +
[[Category: Pardon, E.]]
 +
[[Category: Steyaert, J.]]
 +
[[Category: Swartz, D J.]]
 +
[[Category: Szewczyk, P.]]
 +
[[Category: Urbatsch, I.]]
 +
[[Category: Villaluz, M.]]
 +
[[Category: Ward, A.]]
 +
[[Category: Atp binding]]
 +
[[Category: Membrane]]
 +
[[Category: Membrane protein]]
 +
[[Category: Transport protein]]
 +
[[Category: Transporter]]

Revision as of 05:22, 1 August 2013

Template:STRUCTURE 4ksb

Contents

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Function

[MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.[1]

About this Structure

4ksb is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. ↑ Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science. 2009 Mar 27;323(5922):1718-22. PMID:19325113 doi:323/5922/1718

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ksb"
Personal tools