2hjv
From Proteopedia
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| - | [[Image:2hjv.gif|left|200px]] | + | [[Image:2hjv.gif|left|200px]] |
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| - | '''Structure of the second domain (residues 207-368) of the Bacillus subtilis YxiN protein''' | + | {{Structure |
| + | |PDB= 2hjv |SIZE=350|CAPTION= <scene name='initialview01'>2hjv</scene>, resolution 1.95Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= dbpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis]) | ||
| + | }} | ||
| + | |||
| + | '''Structure of the second domain (residues 207-368) of the Bacillus subtilis YxiN protein''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2HJV is a [ | + | 2HJV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HJV OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN., Caruthers JM, Hu Y, McKay DB, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt, 12):1191-5. Epub 2006 Nov 30. PMID:[http:// | + | Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN., Caruthers JM, Hu Y, McKay DB, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt, 12):1191-5. Epub 2006 Nov 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17142894 17142894] |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: parallel alpha-beta]] | [[Category: parallel alpha-beta]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:18:04 2008'' |
Revision as of 15:18, 20 March 2008
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| , resolution 1.95Å | |||||||
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| Gene: | dbpA (Bacillus subtilis) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of the second domain (residues 207-368) of the Bacillus subtilis YxiN protein
Overview
The Bacillus subtilis RNA helicase YxiN is a modular three-domain protein. The first two domains form a conserved helicase core that couples an ATPase activity to an RNA duplex-destabilization activity, while the third domain recognizes a stem-loop of 23S ribosomal RNA with high affinity and specificity. The structure of the second domain, amino-acid residues 207-368, has been solved to 1.95 A resolution, revealing a parallel alphabeta-fold. The crystallographic asymmetric unit contains two protomers; superposition shows that they differ substantially in two segments of peptide that overlap the conserved helicase sequence motifs V and VI, while the remainder of the domain is isostructural. The conformational variability of these segments suggests that induced fit is intrinsic to the recognition of ligands (ATP and RNA) and the coupling of the ATPase activity to conformational changes.
About this Structure
2HJV is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN., Caruthers JM, Hu Y, McKay DB, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt, 12):1191-5. Epub 2006 Nov 30. PMID:17142894
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