4kwt
From Proteopedia
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| - | + | ==Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution== | |
| - | + | <StructureSection load='4kwt' size='340' side='right' caption='[[4kwt]], [[Resolution|resolution]] 1.86Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[4kwt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_vulnificus_cmcp6 Vibrio vulnificus cmcp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KWT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KWT FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jfr|4jfr]], [[4h31|4h31]], [[4jqo|4jqo]], [[4jhx|4jhx]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argF, VV1_1466 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216895 Vibrio vulnificus CMCP6])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kwt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kwt RCSB], [http://www.ebi.ac.uk/pdbsum/4kwt PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity). | [[http://www.uniprot.org/uniprot/OTC_VIBVU OTC_VIBVU]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity). | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Ornithine carbamoyltransferase|Ornithine carbamoyltransferase]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Ornithine carbamoyltransferase]] | [[Category: Ornithine carbamoyltransferase]] | ||
[[Category: Vibrio vulnificus cmcp6]] | [[Category: Vibrio vulnificus cmcp6]] | ||
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: Bacal, P | + | [[Category: Bacal, P]] |
| - | [[Category: Bajor, J | + | [[Category: Bajor, J]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Grimshaw, S | + | [[Category: Grimshaw, S]] |
| - | [[Category: Minor, W | + | [[Category: Minor, W]] |
| - | [[Category: Shabalin, I G | + | [[Category: Shabalin, I G]] |
| - | [[Category: Winsor, J | + | [[Category: Winsor, J]] |
[[Category: Carbamoyl phosphate]] | [[Category: Carbamoyl phosphate]] | ||
| - | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Citrulline]] | [[Category: Citrulline]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
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[[Category: Ornithine]] | [[Category: Ornithine]] | ||
[[Category: Phosphate]] | [[Category: Phosphate]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 21:25, 24 December 2014
Crystal structure of unliganded anabolic ornithine carbamoyltransferase from Vibrio vulnificus at 1.86 A resolution
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Categories: Ornithine carbamoyltransferase | Vibrio vulnificus cmcp6 | Anderson, W F | Bacal, P | Bajor, J | Structural genomic | Grimshaw, S | Minor, W | Shabalin, I G | Winsor, J | Carbamoyl phosphate | Citrulline | Csgid | National institute of allergy and infectious disease | Niaid | Ornithine | Phosphate | Transferase
