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2lxi
From Proteopedia
(Difference between revisions)
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| - | + | ==NMR structure of the N-terminal RNA Binding domain 1 (RRM1) of the protein RBM10 from Homo sapiens== | |
| - | + | <StructureSection load='2lxi' size='340' side='right' caption='[[2lxi]], [[NMR_Ensembles_of_Models | 19 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Disease== | + | <table><tr><td colspan='2'>[[2lxi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LXI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LXI FirstGlance]. <br> |
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBM10, DXS8237E, GPATC9, GPATCH9, KIAA0122 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lxi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lxi RCSB], [http://www.ebi.ac.uk/pdbsum/2lxi PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> | [[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> | ||
| - | + | == Function == | |
| - | ==Function== | + | |
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> | [[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | <references | + | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Dutta, S K | + | [[Category: Dutta, S K]] |
| - | [[Category: Geralt, M | + | [[Category: Geralt, M]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Serrano, P | + | [[Category: Serrano, P]] |
| - | [[Category: TCELL, Partnership for T-Cell Biology | + | [[Category: TCELL, Partnership for T-Cell Biology]] |
| - | [[Category: Wuthrich, K | + | [[Category: Wuthrich, K]] |
[[Category: Rna binding]] | [[Category: Rna binding]] | ||
[[Category: Rna binding protein]] | [[Category: Rna binding protein]] | ||
Revision as of 05:05, 22 December 2014
NMR structure of the N-terminal RNA Binding domain 1 (RRM1) of the protein RBM10 from Homo sapiens
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