4k4x
From Proteopedia
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{{STRUCTURE_4k4x| PDB=4k4x | SCENE= }} | {{STRUCTURE_4k4x| PDB=4k4x | SCENE= }} | ||
===Coxsackievirus B3 polymerase elongation complex (r2_form), rna=== | ===Coxsackievirus B3 polymerase elongation complex (r2_form), rna=== | ||
| + | {{ABSTRACT_PUBMED_23667424}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[4k4x]] is a 16 chain structure | + | [[4k4x]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4X OCA]. |
| - | + | ||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023667424</ref><references group="xtra"/><references/> | ||
[[Category: Gong, P.]] | [[Category: Gong, P.]] | ||
[[Category: Peersen, O B.]] | [[Category: Peersen, O B.]] | ||
Revision as of 10:26, 3 July 2013
Contents |
Coxsackievirus B3 polymerase elongation complex (r2_form), rna
Template:ABSTRACT PUBMED 23667424
Function
[Q66338_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS001676_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]
About this Structure
4k4x is a 16 chain structure. Full crystallographic information is available from OCA.
Reference
- Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB. Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. PLoS One. 2013 May 8;8(5):e60272. doi: 10.1371/journal.pone.0060272. Print 2013. PMID:23667424 doi:10.1371/journal.pone.0060272
