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4k8d

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{{STRUCTURE_4k8d| PDB=4k8d | SCENE= }}
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==Crystal structure of the C558(464)A/C559(465)A double mutant of Tn501 MerA in complex with NADPH and Hg2+==
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===Crystal structure of the C558(464)A/C559(465)A double mutant of Tn501 MerA in complex with NADPH and Hg2+===
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<StructureSection load='4k8d' size='340' side='right' caption='[[4k8d]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4k8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K8D FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/MERA_PSEAI MERA_PSEAI]] Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k7z|4k7z]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">merA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
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[[4k8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8D OCA].
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mercury(II)_reductase Mercury(II) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.1.1 1.16.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k8d RCSB], [http://www.ebi.ac.uk/pdbsum/4k8d PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Dong, A.]]
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[[Category: Dong, A]]
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[[Category: Falkowski, M.]]
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[[Category: Falkowski, M]]
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[[Category: Malone, M.]]
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[[Category: Malone, M]]
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[[Category: Miller, S M.]]
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[[Category: Miller, S M]]
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[[Category: Pai, E F.]]
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[[Category: Pai, E F]]
[[Category: Flavoenzyme]]
[[Category: Flavoenzyme]]
[[Category: Mercuric ion complex]]
[[Category: Mercuric ion complex]]

Revision as of 15:26, 21 December 2014

Crystal structure of the C558(464)A/C559(465)A double mutant of Tn501 MerA in complex with NADPH and Hg2+

4k8d, resolution 1.86Å

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