Macrophage inhibitory factor
From Proteopedia
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| - | <StructureSection load='2ooh' size='350' side='right' caption='Structure of human macrophage inhibitory factor complex with inhibitor (PDB entry [[2ooh]])' scene=''> | + | <StructureSection load='2ooh' size='350' side='right' caption='Structure of human macrophage inhibitory factor trimer complex with inhibitor, glycerol and sulfate (PDB entry [[2ooh]])' scene=''> |
'''Macrophage inhibitory factor''' (MIF) is an inflammatory cytokine. MIF is released to the blood stream upon stimulation of white blood cells by bacterial antigens. MIF contains two different catalytic sites. A phenylpyruvate tautomerase site is located in the N terminal. A disulfide reductase site is located in the tetrapeptide Cys-Ala-Leu-Cys in position 57-60. | '''Macrophage inhibitory factor''' (MIF) is an inflammatory cytokine. MIF is released to the blood stream upon stimulation of white blood cells by bacterial antigens. MIF contains two different catalytic sites. A phenylpyruvate tautomerase site is located in the N terminal. A disulfide reductase site is located in the tetrapeptide Cys-Ala-Leu-Cys in position 57-60. | ||
Revision as of 09:33, 23 June 2013
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