4isy
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4isy| PDB=4isy | SCENE= }} | |
+ | ===Crystal structure of IscS from Mycobacterium tuberculosis=== | ||
+ | {{ABSTRACT_PUBMED_24548275}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/ISCS_MYCTU ISCS_MYCTU]] Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Participates in the biosynthesis of metalloclusters by providing the inorganic sulfur required for Fe-S core formation. One acceptor is Whib3, on which this enzyme assembles a 4Fe-4S cluster. | ||
- | + | ==About this Structure== | |
+ | [[4isy]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ISY OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:024548275</ref><references group="xtra"/><references/> | ||
+ | [[Category: Cysteine desulfurase]] | ||
+ | [[Category: Cole, S T.]] | ||
+ | [[Category: Pojer, F.]] | ||
+ | [[Category: Rybniker, J.]] | ||
+ | [[Category: Desulfurase]] | ||
+ | [[Category: Plp cofactor]] | ||
+ | [[Category: Transferase]] |
Revision as of 18:14, 3 March 2014
Contents |
Crystal structure of IscS from Mycobacterium tuberculosis
Template:ABSTRACT PUBMED 24548275
Function
[ISCS_MYCTU] Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Participates in the biosynthesis of metalloclusters by providing the inorganic sulfur required for Fe-S core formation. One acceptor is Whib3, on which this enzyme assembles a 4Fe-4S cluster.
About this Structure
4isy is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Rybniker J, Pojer F, Marienhagen J, Kolly GS, Chen JM, van Gumpel E, Hartmann P, Cole ST. The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defense. Biochem J. 2014 Feb 19. PMID:24548275 doi:http://dx.doi.org/10.1042/BJ20130732