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4k2o

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4k2o| PDB=4k2o | SCENE= }}
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===The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain===
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The entry 4k2o is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
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Authors: Joshi, M., Gakhar, L., Fuentes, E.J.
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==About this Structure==
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[[4k2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K2O OCA].
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Description: The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain
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[[Category: Homo sapiens]]
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[[Category: Fuentes, E J.]]
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[[Category: Gakhar, L.]]
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[[Category: Joshi, M.]]
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[[Category: Par-3]]
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[[Category: Ph and coiled coil domain]]
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[[Category: Phosphoinositide binding]]
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[[Category: Protein-protein interaction]]
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[[Category: Signaling protein]]
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[[Category: Tight junction]]

Revision as of 15:53, 10 July 2013

Template:STRUCTURE 4k2o

The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain

Function

[TIAM1_HUMAN] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.

About this Structure

4k2o is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

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