4k2p
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4k2p| PDB=4k2p | SCENE= }} | |
| + | ===The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. | ||
| - | + | ==About this Structure== | |
| - | + | [[4k2p]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K2P OCA]. | |
| - | + | [[Category: Homo sapiens]] | |
| + | [[Category: Fuentes, E J.]] | ||
| + | [[Category: Gakhar, L.]] | ||
| + | [[Category: Joshi, M.]] | ||
| + | [[Category: Par-3]] | ||
| + | [[Category: Ph and coiled coil domain]] | ||
| + | [[Category: Phosphoinositide binding]] | ||
| + | [[Category: Protein-protein interaction]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Tight junction]] | ||
Revision as of 15:53, 10 July 2013
The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain
Function
[TIAM1_HUMAN] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
About this Structure
4k2p is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
