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4kzy

From Proteopedia

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'''Unreleased structure'''
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{{Large structure}}
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{{STRUCTURE_4kzy| PDB=4kzy | SCENE= }}
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===Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.===
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The entry 4kzy is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/G1TN72_RABIT G1TN72_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).[HAMAP-Rule:MF_03122] [[http://www.uniprot.org/uniprot/EIF1_HUMAN EIF1_HUMAN]] Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. [[http://www.uniprot.org/uniprot/IF1AX_HUMAN IF1AX_HUMAN]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
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Authors: Lomakin, I.B., Steitz, T.A.
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==About this Structure==
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[[4kzy]] is a 36 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZY OCA].
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Description: Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
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[[Category: Homo sapiens]]
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[[Category: Oryctolagus cuniculus]]
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[[Category: Lomakin, I B.]]
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[[Category: Steitz, T A.]]
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[[Category: 40]]
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[[Category: Ribosome]]
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[[Category: Translation initiation]]

Revision as of 13:13, 24 July 2013

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Template:STRUCTURE 4kzy

Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.

Function

[G1TN72_RABIT] May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).[HAMAP-Rule:MF_03122] [EIF1_HUMAN] Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. [IF1AX_HUMAN] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

About this Structure

4kzy is a 36 chain structure with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA.

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OCA

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