4lf3

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m (Protected "4lf3" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4lf3| PDB=4lf3 | SCENE= }}
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===Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor===
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The entry 4lf3 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN]] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
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Authors: Murray, J.M., Mukund, S.
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==About this Structure==
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[[4lf3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LF3 OCA].
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Description: Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
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[[Category: Mukund, S.]]
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[[Category: Murray, J M.]]
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[[Category: Fab fragment]]
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[[Category: Gcgr]]
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[[Category: Immune system]]

Revision as of 08:29, 13 November 2013

Template:STRUCTURE 4lf3

Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor

Function

[GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

About this Structure

4lf3 is a 6 chain structure. Full crystallographic information is available from OCA.

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OCA

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