2m10
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_2m10| PDB=2m10 | SCENE= }} | {{STRUCTURE_2m10| PDB=2m10 | SCENE= }} | ||
===trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative=== | ===trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative=== | ||
| + | {{ABSTRACT_PUBMED_23818626}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:023818626</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
Revision as of 04:35, 18 July 2013
Contents |
trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Template:ABSTRACT PUBMED 23818626
Function
[PTN13_HUMAN] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.[1]
About this Structure
2m10 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Buchli B, Waldauer SA, Walser R, Donten ML, Pfister R, Blochliger N, Steiner S, Caflisch A, Zerbe O, Hamm P. Kinetic response of a photoperturbed allosteric protein. Proc Natl Acad Sci U S A. 2013 Jul 1. PMID:23818626 doi:10.1073/pnas.1306323110
- ↑ Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM. Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket. J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20. PMID:15611135 doi:10.1074/jbc.M412211200
