Outer surface protein
From Proteopedia
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{{STRUCTURE_2af5| PDB=2af5 | SIZE=400| SCENE= |right|CAPTION=Outer surface protein A, [[2af5]] }} | {{STRUCTURE_2af5| PDB=2af5 | SIZE=400| SCENE= |right|CAPTION=Outer surface protein A, [[2af5]] }} | ||
| - | ==3D structures of outer surface protein== | ||
'''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | '''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | ||
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*[[OspC and Binding]]<br /> | *[[OspC and Binding]]<br /> | ||
*[[G18secL03Tpc4]]. | *[[G18secL03Tpc4]]. | ||
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| + | ==3D structures of outer surface protein== | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===OspA=== | ===OspA=== | ||
Revision as of 08:28, 4 July 2013
Outer surface proteins (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. OspA contributes to the colonization of the gut by the bacteria. OspC is a major antigen on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:
OspA -
OspB -
OspC -
Contents |
3D structures of outer surface protein
Updated on 04-July-2013
OspA
1osp, 1fj1 – OspA (mutant) + antibody – Borrelia burgdorferi
2af5, 2fkg, 2fkj, 2hkd – OspA
2g8c, 2i5z, 2ol6, 2ol7, 2ol8, 2oy1, 2i5v, 2oy5, 2oy7, 2oy8 - OspA (mutant)
OspB
1p4p – OspB C terminal
1rjl - OspB+ antibody
OspC
1ggq, 1g5z – OspC
1f1m – OspC (mutant)
