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DNA damage-binding protein
From Proteopedia
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[[Image:3ei1.png|left|200px|thumb|Crystal structure of human DDB1 (grey) and DDB2 (green) complex with DNA [[3ei1]]]] | [[Image:3ei1.png|left|200px|thumb|Crystal structure of human DDB1 (grey) and DDB2 (green) complex with DNA [[3ei1]]]] | ||
{{STRUCTURE_3ei1| PDB=3ei1 | SIZE=350| SCENE= |right|CAPTION=Human DDB1 (grey) and DDB2 (green) complex with DNA, TMP and tetraethylene glycol [[3ei1]] }} | {{STRUCTURE_3ei1| PDB=3ei1 | SIZE=350| SCENE= |right|CAPTION=Human DDB1 (grey) and DDB2 (green) complex with DNA, TMP and tetraethylene glycol [[3ei1]] }} | ||
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Revision as of 10:39, 4 July 2013
DNA damage-binding protein (DDB) functions in nucleotide excision repair. It prevents UV damage to DNA. DDB is a heterodimer composed of the large DDB1 and the smaller DNA-binding DDB2.
3D Structures of DNA damage-binding protein
Updated on 04-July-2013
DDB1
2b5l – hDDB + simian virus 5 protein – human
2b5m – hDDB
2b5m, 2b5n – hDDB BPB domain
2hye – hDDB + simian virus 5 protein + cullin-4A + ring-box protein 1
3e0c – hDDB
3i7h, 3i7k, 3i7l, 3i7n, 3i7o, 3i7p, 3i89, 3i8c, 3i8e – hDDB + X protein peptide
4a11 – hDDB + DNA excision repair protein ERCC-8
DDB1+DDB2
3ei1, 3ei2, 4a08, 4a09, 4a0a, 4a0b, 4e54, 4e5z – hDDB + DNA
3ei3, 3ei4 – hDDB
4a0k – hDDB + cullin-4A + ring-box protein 1
4a0l – hDDB + cullin-4A + ring-box protein 1 + DNA
