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4h24
From Proteopedia
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{{STRUCTURE_4h24| PDB=4h24 | SCENE= }} | {{STRUCTURE_4h24| PDB=4h24 | SCENE= }} | ||
| - | ===Cytochrome | + | ===Cytochrome P450BM3-CIS cyclopropanation catalyst=== |
{{ABSTRACT_PUBMED_23792734}} | {{ABSTRACT_PUBMED_23792734}} | ||
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[Cytochrome P450|Cytochrome P450]] | ||
| + | *[[NADPH-Cytochrome P450 Reductase|NADPH-Cytochrome P450 Reductase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:023792734</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:023792734</ref><references group="xtra"/><references/> | ||
| - | [[Category: | + | [[Category: Atcc 14581]] |
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
[[Category: Arnold, F H.]] | [[Category: Arnold, F H.]] | ||
Revision as of 08:10, 18 December 2013
Contents |
Cytochrome P450BM3-CIS cyclopropanation catalyst
Template:ABSTRACT PUBMED 23792734
Function
[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.
About this Structure
4h24 is a 4 chain structure with sequence from Atcc 14581. Full crystallographic information is available from OCA.
See Also
Reference
- Coelho PS, Wang ZJ, Ener ME, Baril SA, Kannan A, Arnold FH, Brustad EM. A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo. Nat Chem Biol. 2013 Jun 23. doi: 10.1038/nchembio.1278. PMID:23792734 doi:10.1038/nchembio.1278
