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4hpw

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'''Unreleased structure'''
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{{STRUCTURE_4hpw| PDB=4hpw | SCENE= }}
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===Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine===
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The entry 4hpw is ON HOLD until Oct 24 2014
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==Function==
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[[http://www.uniprot.org/uniprot/SYY_METJA SYY_METJA]] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>
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Authors: Yang, Y., Zhou, Q., Dong, J., Li, J., Xiaoxuan, L., Mukherjee, A., Ouyang, H., Nilges, M., Li, H., Gao, F., Gong, W., Lu, Y., Wang, J.
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==About this Structure==
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[[4hpw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA].
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Description: Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Methanocaldococcus jannaschii dsm 2661]]
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[[Category: Tyrosine--tRNA ligase]]
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[[Category: Dong, J.]]
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[[Category: Gao, F.]]
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[[Category: Gong, W.]]
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[[Category: Li, H.]]
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[[Category: Li, J.]]
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[[Category: Lu, Y.]]
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[[Category: Mukherjee, A.]]
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[[Category: Nilges, M.]]
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[[Category: Ouyang, H.]]
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[[Category: Wang, J.]]
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[[Category: Xiaoxuan, L.]]
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[[Category: Yang, Y.]]
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[[Category: Zhou, Q.]]
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[[Category: 3-o-methyl tyrosine incorporation]]
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[[Category: Ligase]]
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[[Category: Trna]]

Revision as of 09:50, 30 October 2013

Template:STRUCTURE 4hpw

Contents

Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine

Function

[SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[1]

About this Structure

4hpw is a 1 chain structure with sequence from Methanocaldococcus jannaschii dsm 2661. Full crystallographic information is available from OCA.

Reference

  1. ↑ Steer BA, Schimmel P. Major anticodon-binding region missing from an archaebacterial tRNA synthetase. J Biol Chem. 1999 Dec 10;274(50):35601-6. PMID:10585437

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