2ymt
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_2ymt| PDB=2ymt | SCENE= }} | {{STRUCTURE_2ymt| PDB=2ymt | SCENE= }} | ||
===gamma 2 adaptin EAR domain crystal structure with phage peptide GEEWGPWV=== | ===gamma 2 adaptin EAR domain crystal structure with phage peptide GEEWGPWV=== | ||
| + | {{ABSTRACT_PUBMED_23851574}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:023851574</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ashcroft, A.]] | [[Category: Ashcroft, A.]] | ||
Revision as of 11:24, 24 July 2013
Contents |
gamma 2 adaptin EAR domain crystal structure with phage peptide GEEWGPWV
Template:ABSTRACT PUBMED 23851574
Function
[AP1G2_HUMAN] May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).[1] [2] [3]
About this Structure
2ymt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Jurgens MC, Voros J, Rautureau GJ, Shepherd DA, Pye VE, Muldoon J, Johnson CM, Ashcroft AE, Freund SM, Ferguson N. The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry. Nat Chem Biol. 2013 Jul 14. doi: 10.1038/nchembio.1294. PMID:23851574 doi:10.1038/nchembio.1294
- ↑ Takatsu H, Sakurai M, Shin HW, Murakami K, Nakayama K. Identification and characterization of novel clathrin adaptor-related proteins. J Biol Chem. 1998 Sep 18;273(38):24693-700. PMID:9733768
- ↑ Rost M, Mann S, Lambert C, Doring T, Thome N, Prange R. Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation. J Biol Chem. 2006 Sep 29;281(39):29297-308. Epub 2006 Jul 25. PMID:16867982 doi:M603517200
- ↑ Lambert C, Doring T, Prange R. Hepatitis B virus maturation is sensitive to functional inhibition of ESCRT-III, Vps4, and gamma 2-adaptin. J Virol. 2007 Sep;81(17):9050-60. Epub 2007 Jun 6. PMID:17553870 doi:JVI.00479-07
