4b8r
From Proteopedia
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{{STRUCTURE_4b8r| PDB=4b8r | SCENE= }} | {{STRUCTURE_4b8r| PDB=4b8r | SCENE= }} | ||
===Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)=== | ===Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)=== | ||
| + | {{ABSTRACT_PUBMED_23818958}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:023818958</ref><references group="xtra"/><references/> |
[[Category: ADP-specific glucokinase]] | [[Category: ADP-specific glucokinase]] | ||
[[Category: Thermococcus litoralis]] | [[Category: Thermococcus litoralis]] | ||
Revision as of 04:36, 18 July 2013
Contents |
Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)
Template:ABSTRACT PUBMED 23818958
Function
[GLKA_THELI] Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. Can also use CDP as the phosphoryl group donor and D-glucosamine and D-1,5-anhydroglucitol as the phosphoryl group acceptor.[1]
About this Structure
4b8r is a 1 chain structure with sequence from Thermococcus litoralis. Full crystallographic information is available from OCA.
Reference
- Rivas-Pardo JA, Herrera-Morande A, Castro-Fernandez V, Fernandez FJ, Vega MC, Guixe V. Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis. PLoS One. 2013 Jun 20;8(6):e66687. doi: 10.1371/journal.pone.0066687. Print 2013. PMID:23818958 doi:10.1371/journal.pone.0066687
- ↑ Koga S, Yoshioka I, Sakuraba H, Takahashi M, Sakasegawa S, Shimizu S, Ohshima T. Biochemical characterization, cloning, and sequencing of ADP-dependent (AMP-forming) glucokinase from two hyperthermophilic archaea, Pyrococcus furiosus and Thermococcus litoralis. J Biochem. 2000 Dec;128(6):1079-85. PMID:11098152
