4lcf
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4lcf| PDB=4lcf | SCENE= }} | |
+ | ===Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex=== | ||
+ | {{ABSTRACT_PUBMED_23914798}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | ||
- | + | ==About this Structure== | |
+ | [[4lcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCF OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:023914798</ref><references group="xtra"/><references/> | ||
+ | [[Category: Pseudomonas aeruginosa pao1]] | ||
+ | [[Category: Lee, C J.]] | ||
+ | [[Category: Zhou, P.]] | ||
+ | [[Category: Acyl udp-glcnac]] | ||
+ | [[Category: Baab sandwich]] | ||
+ | [[Category: Deacetylation]] | ||
+ | [[Category: Hydrolase-antibiotic complex]] | ||
+ | [[Category: Hydroxamate]] | ||
+ | [[Category: Lipid a biosynthesis]] | ||
+ | [[Category: Lipid a synthesis]] | ||
+ | [[Category: Lpxc]] |
Revision as of 08:22, 21 August 2013
Contents |
Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex
Template:ABSTRACT PUBMED 23914798
Function
[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
About this Structure
4lcf is a 1 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
- Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure and antibiotic activity of aryl-substituted LpxC inhibitors. J Med Chem. 2013 Aug 5. PMID:23914798 doi:10.1021/jm4007774