4kzy
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4kzy| PDB=4kzy | SCENE= }} | {{STRUCTURE_4kzy| PDB=4kzy | SCENE= }} | ||
===Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.=== | ===Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.=== | ||
| + | {{ABSTRACT_PUBMED_23873042}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4kzy]] is a 36 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZY OCA]. | [[4kzy]] is a 36 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZY OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023873042</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
Revision as of 19:29, 7 August 2013
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Contents |
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
Template:ABSTRACT PUBMED 23873042
Function
[G1TN72_RABIT] May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).[HAMAP-Rule:MF_03122] [EIF1_HUMAN] Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA. [IF1AX_HUMAN] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
About this Structure
4kzy is a 36 chain structure with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA.
Reference
- Lomakin IB, Steitz TA. The initiation of mammalian protein synthesis and mRNA scanning mechanism. Nature. 2013 Jul 21. doi: 10.1038/nature12355. PMID:23873042 doi:10.1038/nature12355
