Sandbox 126
From Proteopedia
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==Background== | ==Background== | ||
| - | PBP2a is composed of two domains: | + | PBP2a is composed of two domains: <scene name='37/372726/Tp_and_npb_domain/1'>a non-penicillin binding (NPB) domain and a TP domain.</scene> The NBP domain of PBP2a is anchored in the cell membrane, while the TP domain “sits” in the periplasm with its active site facing the inner surface of the cell wall. The active site contains a serine residue at position 403 ('''Ser403''') which catalyzes the cross-linking of the peptidoglycan rows with pentaglycine cross-links. |
<scene name='37/372726/Pbp2a_with_residues/1'>PBP2a and active site residues</scene> | <scene name='37/372726/Pbp2a_with_residues/1'>PBP2a and active site residues</scene> | ||
<scene name='37/372726/Close_up_of_active_site/2'>Close up of active site</scene> | <scene name='37/372726/Close_up_of_active_site/2'>Close up of active site</scene> | ||
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==How does PBP2a work== | ==How does PBP2a work== | ||
Revision as of 17:39, 29 July 2013
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