2ma6

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{{STRUCTURE_2ma6| PDB=2ma6 | SCENE= }}
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==Solution NMR Structure of the RING finger domain from the Kip1 ubiquitination-promoting E3 complex protein 1 (KPC1/RNF123) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8700A==
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===Solution NMR Structure of the RING finger domain from the Kip1 ubiquitination-promoting E3 complex protein 1 (KPC1/RNF123) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8700A===
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<StructureSection load='2ma6' size='340' side='right' caption='[[2ma6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2ma6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MA6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FP1477, KPC1, RNF123 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ma6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ma6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ma6 PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/RN123_HUMAN RN123_HUMAN]] Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.<ref>PMID:15531880</ref> <ref>PMID:16227581</ref>
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*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2ma6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MA6 OCA].
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T B.]]
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[[Category: Acton, T B]]
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[[Category: Everett, J K.]]
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[[Category: Everett, J K]]
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[[Category: Janjua, H.]]
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[[Category: Janjua, H]]
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[[Category: Kennedy, M A.]]
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[[Category: Kennedy, M A]]
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[[Category: Kohan, E.]]
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[[Category: Kohan, E]]
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[[Category: Montelione, G T.]]
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[[Category: Montelione, G T]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot, T A]]
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[[Category: Wang, H.]]
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[[Category: Wang, H]]
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[[Category: Xiao, R.]]
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[[Category: Xiao, R]]
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[[Category: Yang, Y.]]
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[[Category: Yang, Y]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Nesg]]
[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
[[Category: Psi-biology]]
[[Category: Ring fing domain]]
[[Category: Ring fing domain]]
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[[Category: Structural genomic]]
 
[[Category: Zinc binding protein]]
[[Category: Zinc binding protein]]

Revision as of 12:33, 18 December 2014

Solution NMR Structure of the RING finger domain from the Kip1 ubiquitination-promoting E3 complex protein 1 (KPC1/RNF123) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8700A

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