4iz6
From Proteopedia
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{{STRUCTURE_4iz6| PDB=4iz6 | SCENE= }} | {{STRUCTURE_4iz6| PDB=4iz6 | SCENE= }} | ||
===Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry=== | ===Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry=== | ||
| + | {{ABSTRACT_PUBMED_23897471}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4iz6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZ6 OCA]. | [[4iz6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZ6 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023897471</ref><references group="xtra"/><references/> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Gulick, A M.]] | [[Category: Gulick, A M.]] | ||
Revision as of 04:49, 10 October 2013
Contents |
Structure of EntE and EntB, an NRPS adenylation-PCP fusion protein with pseudo translational symmetry
Template:ABSTRACT PUBMED 23897471
Function
[ENTE_ECOLI] Activates the carboxylate group of 2,3-dihydroxy-benzoate (2,3-DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate. Then, catalyzes the acylation of holo-EntB with 2,3-DHB adenylate, preparing that molecule for amide bond formation with L-serine.
About this Structure
4iz6 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Sundlov JA, Gulick AM. Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1482-92. doi:, 10.1107/S0907444913009372. Epub 2013 Jul 18. PMID:23897471 doi:http://dx.doi.org/10.1107/S0907444913009372
Categories: Escherichia coli | Gulick, A M. | Sundlov, J A. | 4'phosphopantetheinylation cofactor 4'pp | Acyl carrier protein | Adenylate-forming enzyme | Anl superfamily | Chimera protein | Fusion protein | Ligase | Non-ribosomal peptide synthetase | Nrps adenylation domains and acyl carrier protein domain | Pseudo-translational symmetry
