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4i74

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{{STRUCTURE_4i74| PDB=4i74 | SCENE= }}
{{STRUCTURE_4i74| PDB=4i74 | SCENE= }}
===Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion===
===Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion===
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{{ABSTRACT_PUBMED_16630632}}
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{{ABSTRACT_PUBMED_23897478}}
==About this Structure==
==About this Structure==
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[[4i74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_strain_927/4_gutat10.1 Trypanosoma brucei brucei strain 927/4 gutat10.1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I74 OCA].
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[[4i74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I74 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:016630632</ref><references group="xtra"/><references/>
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<ref group="xtra">PMID:023897478</ref><references group="xtra"/><references/>
[[Category: Purine nucleosidase]]
[[Category: Purine nucleosidase]]
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[[Category: Trypanosoma brucei brucei strain 927/4 gutat10 1]]
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[[Category: Tryb2]]
[[Category: Degano, M.]]
[[Category: Degano, M.]]
[[Category: Giannese, F.]]
[[Category: Giannese, F.]]

Revision as of 08:07, 18 December 2013

Template:STRUCTURE 4i74

Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion

Template:ABSTRACT PUBMED 23897478

About this Structure

4i74 is a 1 chain structure with sequence from Tryb2. Full crystallographic information is available from OCA.

Reference

  • Giannese F, Berg M, Van der Veken P, Castagna V, Tornaghi P, Augustyns K, Degano M. Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1553-66. doi:, 10.1107/S0907444913010792. Epub 2013 Jul 20. PMID:23897478 doi:http://dx.doi.org/10.1107/S0907444913010792

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