This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4foa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_4foa| PDB=4foa | SCENE= }}
+
==Crystal Structure of the Mtb ThyA in Complex with 5-fluoro-dUMP==
-
===Crystal Structure of the Mtb ThyA in Complex with 5-fluoro-dUMP===
+
<StructureSection load='4foa' size='340' side='right' caption='[[4foa]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4foa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FOA FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UFP:5-FLUORO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>UFP</scene></td></tr>
 +
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qj7|3qj7]], [[4fog|4fog]], [[4fox|4fox]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT2834, MTV002.29c, Rv2764c, thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4foa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4foa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4foa RCSB], [http://www.ebi.ac.uk/pdbsum/4foa PDBsum]</span></td></tr>
 +
</table>
-
==Function==
+
==See Also==
-
[[http://www.uniprot.org/uniprot/TYSY_MYCTU TYSY_MYCTU]] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
+
*[[Thymidylate synthase|Thymidylate synthase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[4foa]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOA OCA].
+
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
-
[[Category: Bruning, J B.]]
+
[[Category: Bruning, J B]]
-
[[Category: Reddy, M C.M.]]
+
[[Category: Reddy, M C.M]]
-
[[Category: Sacchettini, J C.]]
+
[[Category: Sacchettini, J C]]
-
[[Category: TBSGC, TB Structural Genomics Consortium.]]
+
[[Category: Structural genomic]]
[[Category: Structural genomic]]
-
[[Category: Tb structural genomics consortium]]
 
[[Category: Tbsgc]]
[[Category: Tbsgc]]
-
[[Category: Thymidylate synthase]]
 
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 10:44, 21 December 2014

Crystal Structure of the Mtb ThyA in Complex with 5-fluoro-dUMP

4foa, resolution 2.25Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools