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4kn0
From Proteopedia
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{{STRUCTURE_4kn0| PDB=4kn0 | SCENE= }} | {{STRUCTURE_4kn0| PDB=4kn0 | SCENE= }} | ||
===Human folate receptor beta (FOLR2) in complex with the antifolate methotrexate=== | ===Human folate receptor beta (FOLR2) in complex with the antifolate methotrexate=== | ||
| + | {{ABSTRACT_PUBMED_23934049}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4kn0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KN0 OCA]. | [[4kn0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KN0 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023934049</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: III, C E.Dann.]] | [[Category: III, C E.Dann.]] | ||
Revision as of 06:17, 2 October 2013
Contents |
Human folate receptor beta (FOLR2) in complex with the antifolate methotrexate
Template:ABSTRACT PUBMED 23934049
Function
[FOLR2_HUMAN] Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
About this Structure
4kn0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE 3rd. Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15180-8. doi:, 10.1073/pnas.1308827110. Epub 2013 Aug 9. PMID:23934049 doi:10.1073/pnas.1308827110
