2jf9
From Proteopedia
Line 1: | Line 1: | ||
- | [[Image:2jf9.gif|left|200px]] | + | [[Image:2jf9.gif|left|200px]] |
- | + | ||
- | '''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST''' | + | {{Structure |
+ | |PDB= 2jf9 |SIZE=350|CAPTION= <scene name='initialview01'>2jf9</scene>, resolution 2.10Å | ||
+ | |SITE= <scene name='pdbsite=AC1:Ca+Binding+Site+For+Chain+R'>AC1</scene> | ||
+ | |LIGAND= <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST''' | ||
+ | |||
==Disease== | ==Disease== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
- | 2JF9 is a [ | + | 2JF9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JF9 OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
Line 38: | Line 47: | ||
[[Category: zinc-finger]] | [[Category: zinc-finger]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:41:06 2008'' |
Revision as of 15:41, 20 March 2008
| |||||||
, resolution 2.10Å | |||||||
---|---|---|---|---|---|---|---|
Sites: | |||||||
Ligands: | , , and | ||||||
Coordinates: | save as pdb, mmCIF, xml |
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST
Disease
Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]
About this Structure
2JF9 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:41:06 2008
Categories: Homo sapiens | Single protein | Gustafsson, J A. | Heldring, N. | Mcdonnell, D. | Pawson, T. | Pike, A C.W. | Treuter, E. | BCT | CA | EDO | OHT | Alternative splicing | Dna-binding | Ligand-binding domain (lbd) | Lipid-binding | Metal-binding | Nuclear protein | Nuclear receptor | Peptide antagonist | Phosphorylation | Polymorphism | Receptor | Steroid-binding | Transcription | Transcription factor | Transcription regulation | Zinc | Zinc-finger