Transcription initiation factor
From Proteopedia
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<StructureSection load='1vol' size='400' side='right' caption='Structure of human TFIIB (grey) complex with TATA-binding protein (green) and DNA (PDB entry [[1vol]])' scene=''> | <StructureSection load='1vol' size='400' side='right' caption='Structure of human TFIIB (grey) complex with TATA-binding protein (green) and DNA (PDB entry [[1vol]])' scene=''> | ||
| - | '''Transcription initiation factors''' (TFII) are proteins which enable RNA polymerase II to bind to the DNA template in order to start the transcription process. | + | '''Transcription initiation factors''' (TFII) are proteins which enable RNA polymerase II to bind to the DNA template in order to start the transcription process.<br /> |
| + | * '''TFIIA''' is one of several TFs which are required for transcription. TFIIA aids in binding the TATA-binding protein (TBP) to the TATA box containing sequence of the DNA.<br /> | ||
| + | * '''TFIIB''' bridges between TFIID and RNA polymerase II.<br /> | ||
| + | * '''TFIID''' recognizes the promoter sequence on the DNA.<br /> | ||
| + | * '''TFIIF''' binds RNA polymerase III prohibiting it to bind to DNA outside the promoter. | ||
==3D structures of transcription initiation factors== | ==3D structures of transcription initiation factors== | ||
Revision as of 06:47, 21 August 2014
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