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2jhc

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[[Image:2jhc.gif|left|200px]]<br /><applet load="2jhc" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2jhc.gif|left|200px]]
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caption="2jhc, resolution 3.00&Aring;" />
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'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''<br />
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{{Structure
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|PDB= 2jhc |SIZE=350|CAPTION= <scene name='initialview01'>2jhc</scene>, resolution 3.00&Aring;
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|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2JHC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)] with <scene name='pdbligand=GUN:'>GUN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA].
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2JHC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus_10_(isolate_usa) Bluetongue virus 10 (isolate usa)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA].
==Reference==
==Reference==
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Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17417654 17417654]
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Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654]
[[Category: Bluetongue virus 10 (isolate usa)]]
[[Category: Bluetongue virus 10 (isolate usa)]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: virion protein]]
[[Category: virion protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:03:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:41:56 2008''

Revision as of 15:41, 20 March 2008

Image:2jhc.gif


PDB ID 2jhc

Drag the structure with the mouse to rotate
, resolution 3.00Å
Sites:
Ligands:
Coordinates: save as pdb, mmCIF, xml



THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE


Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this Structure

2JHC is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654

Page seeded by OCA on Thu Mar 20 17:41:56 2008

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