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4m63

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'''Unreleased structure'''
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{{STRUCTURE_4m63| PDB=4m63 | SCENE= }}
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===Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL===
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{{ABSTRACT_PUBMED_21873984}}
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The entry 4m63 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/ACT1_DROME ACT1_DROME]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
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Authors: Tomchick, D.R., Zahm, J.A., Rosen, M.K.
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==About this Structure==
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[[4m63]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [http://en.wikipedia.org/wiki/Vibrio_parahaemolyticus_bb22op Vibrio parahaemolyticus bb22op]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M63 OCA].
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Description: Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
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==Reference==
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<ref group="xtra">PMID:021873984</ref><references group="xtra"/><references/>
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[[Category: Adenosinetriphosphatase]]
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[[Category: Drosophila melanogaster]]
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[[Category: Vibrio parahaemolyticus bb22op]]
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[[Category: Rosen, M K.]]
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[[Category: Tomchick, D R.]]
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[[Category: Zahm, J A.]]
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[[Category: Actin nucleation]]
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[[Category: Actin nucleator]]
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[[Category: Actin-binding protein]]
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[[Category: Atp-binding protein]]
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[[Category: Cytoskeleton]]
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[[Category: Hydrolase]]
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[[Category: Vopl c-terminal domain]]
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[[Category: Wasp homology 2 domain]]

Revision as of 06:40, 23 October 2013

Template:STRUCTURE 4m63

Contents

Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL

Template:ABSTRACT PUBMED 21873984

Function

[ACT1_DROME] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.

About this Structure

4m63 is a 5 chain structure with sequence from Drosophila melanogaster and Vibrio parahaemolyticus bb22op. Full crystallographic information is available from OCA.

Reference

  • Yu B, Cheng HC, Brautigam CA, Tomchick DR, Rosen MK. Mechanism of actin filament nucleation by the bacterial effector VopL. Nat Struct Mol Biol. 2011 Aug 28;18(9):1068-74. doi: 10.1038/nsmb.2110. PMID:21873984 doi:10.1038/nsmb.2110

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