4b4x

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{{STRUCTURE_4b4x| PDB=4b4x | SCENE= }}
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==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor==
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===Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor===
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<StructureSection load='4b4x' size='340' side='right' caption='[[4b4x]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4b4x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actsp Actsp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4X FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HQZ:TRIHYDROXY{(1S)-1-[(METHYLSULFONYL)AMINO]ETHYL}BORATE(1-)'>HQZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w79|1w79]], [[1w8q|1w8q]], [[1w8y|1w8y]], [[2vgj|2vgj]], [[2vgk|2vgk]], [[2wke|2wke]], [[2xdm|2xdm]], [[2xk1|2xk1]], [[2xln|2xln]], [[2y4a|2y4a]], [[2y55|2y55]], [[2y59|2y59]], [[3zvt|3zvt]], [[3zvw|3zvw]]</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>
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[[4b4x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomadura_sp_r39 Actinomadura sp r39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4X OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b4x RCSB], [http://www.ebi.ac.uk/pdbsum/4b4x PDBsum]</span></td></tr>
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[[Category: Actinomadura sp r39]]
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</table>
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__TOC__
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</StructureSection>
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[[Category: Actsp]]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
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[[Category: Cannella, S E.]]
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[[Category: Cannella, S E]]
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[[Category: Charlier, P.]]
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[[Category: Charlier, P]]
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[[Category: Herman, R.]]
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[[Category: Herman, R]]
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[[Category: Kerff, F.]]
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[[Category: Kerff, F]]
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[[Category: Rocaboy, M.]]
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[[Category: Rocaboy, M]]
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[[Category: Sauvage, E.]]
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[[Category: Sauvage, E]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Peptidoglycan]]
[[Category: Peptidoglycan]]

Revision as of 09:53, 21 December 2014

Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor

4b4x, resolution 2.65Å

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